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. 2020 Jul 23;8:828. doi: 10.3389/fbioe.2020.00828

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Copyright © 2020 Min, Yoo, Lee, Seo and Kim.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Comparative genomics with 112 E. faecium strains. (A) Hierarchical clustering based on ANI values of 112 E. faecium strains. (B) BIOPOP-3 WT strain was clustered with nine other E. faecium strains. (C) The three COG functional terms significantly differed between the inner-group containing BIOPOP-3 and the rest of E. faecium strains. (D) Pan and core genome estimates of 10 E. faecium strains in the inner-group containing BIOPOP-3. (E) The number of newly identified genes observed when new genomes are added sequentially.