Table I.
Potency relative to hydrocortisone | Half-life | ||||
---|---|---|---|---|---|
Treatments | Equivalent glucocorticoid, mg | Anti-inflammatory | MC | Plasma, min | Duration of action, h |
Short acting | |||||
Hydrocortisone | 20 | 1 | 1 | 90 | 8-12 |
Cortef, Cortisol | 25 | 0.8 | 0.8 | 30 | 8-12 |
Intermediate-acting | |||||
Prednisone | 5 | 4 | 0.8 | 60 | 12-36 |
Prednisolone | 5 | 4 | 0.8 | 200 | 12-36 |
Triamcinolone | 4 | 5 | 0 | 300 | 12-36 |
Methylprednisolone | 4 | 5 | 0.5 | 180 | 12-36 |
Long-acting | |||||
Dexamethasone | 0.75 | 30 | 0 | 200 | 36-54 |
Betamethasone | 0.6 | 30 | 0 | 300 | 36-54 |
Mineralocorticoid | |||||
Fludrocortisone | 0 | 15 | 150 | 240 | 24-36 |
Aldosterone | 0 | 0 | 400+ | 20 | - |
Cortef, generic name for hydrocortisone.