TABLE 1.
BLCA median parameter estimates and 95% CrIs obtained from three Leptospira diagnostic test results in California sea lions (left)
| BLCA Estimates from California sea lion data | Values selected for CSL simulated data | CSL simulated data | |
|---|---|---|---|
| Prevalence (π) | 20.2% (15.6−25.5%) | 20% | 20.6% (15.8−26.2%) |
| Sensitivity – MAT (Se1) | 64.4% (52.0−78.1%) | 65% | 64.0% (50.5−76.6%) |
| Sensitivity – SC (Se2) | 61.1% (48.2−74.3%) | 61% | 60.0% (46.7−72.7%) |
| Sensitivity – PCR (Se3) | 96.0% (86.4−99.9%) | 96% | 93.9% (90.3−99.6%) |
| Specificity – MAT (Sp1) | 98.1% (95.8−99.6%) | 98% | 98.0% (95.3−99.7%) |
| Specificity – SC (Sp2) | 93.2% (89.6−96.3%) | 93% | 92.9% (89.0−99.7%) |
| Specificity – PCR (Sp3) | NA (fixed at 97.2%) | Fixed at 97.2% | NA (fixed at 97.2%) |
These estimated values were chosen as set values for a CSL data simulation (middle). BLCA parameter estimates were then calculated from this simulated CSL data to see how well the model performed (right).