Fig. 5.

Macroscopic sequelae upon Campylobacter infection of conventional mice. Conventionally colonized C57BL/6 mice were perorally infected with C. jejuni (Cj; open circles) or C. coli (Cc; closed circles) on day (d) 0 and d1 by gavage. (A) Immediately before and at defined time points after Campylobacter infection the clinical conditions of mice were quantitatively assessed applying a standardized clinical scoring system (see methods). (B) Upon necrospy (i.e., d21 post-infection) the colonic lengths were measured (in cm). Medians (black bars), levels of significance (P-values) assessed by the Mann Whitney U test and numbers of analyzed animals (in parentheses) are indicated. Data were pooled from four independent experiments