Table 2.
Correlations between clinicopathological parameters and STAS in SQCC
| Parameters | In total | STAS | p | |
|---|---|---|---|---|
| Positive(n(%)) | Negative(n(%)) | |||
| In total | 121 | 39(32.2) | 82(67.8) | |
| Gender | ||||
| Female | 2 | 0(0) | 2(2.4) | 1.000 |
| Male | 119 | 39(100.0) | 80(97.6) | |
| Age | ||||
| ≤ 65 | 38 | 15(38.5) | 23(28.0) | 0.249 |
| > 65 | 83 | 24(61.5) | 59(72.0) | |
| Smoking history | ||||
| Non-smoker | 6 | 0(0) | 6(7.3) | 0.175 |
| Smoker | 115 | 39(100.0) | 76(92.7) | |
| Tumor size | ||||
| ≤ 3 cm | 37 | 12(30.8) | 25(30.5) | 0.975 |
| > 3 cm | 84 | 27(69.2) | 57(69.5) | |
| Pleural invasion | ||||
| Absent | 82 | 28(71.8) | 54(65.9) | 0.513 |
| Present | 39 | 11(28.2) | 28(34.1) | |
| Vascular invasion | ||||
| Absent | 89 | 25(64.1) | 64(78.0) | 0.104 |
| Present | 32 | 14(35.9) | 18(22.0) | |
| Lymphatic invasion | ||||
| Absent | 68 | 16(41.0) | 52(63.4) | 0.020 |
| Present | 53 | 23(59.0) | 30(36.6) | |
| Perineural invasion | ||||
| Absent | 103 | 30(76.9) | 73(89.0) | 0.080 |
| Present | 18 | 9(23.1) | 9(11.0) | |
| Tumor necrosis | ||||
| Absent | 12 | 3(7.7) | 9(11.0) | 0.750 |
| Present | 109 | 36(92.3) | 73(89.0) | |
| Tumor relapse | ||||
| Absent | 89 | 29(74.4) | 60(73.2) | 0.890 |
| Present | 32 | 10(25.6) | 22(26.8) | |
| Pathological stage | ||||
| Stage I-II | 89 | 26(66.7) | 63(76.8) | 0.236* |
| StageIA | 28 | 8(20.5) | 20(24.4) | 0.443 |
| StageIB | 21 | 4(10.3) | 17(20.7) | |
| StageIIA | 26 | 11(28.2) | 15(18.3) | 0.299 |
| StageIIB | 14 | 3(7.7) | 11(13.4) | |
| Stage III-IV | 32 | 13(33.3) | 19(23.2) | |
*Correlation between stage I-II and stage III-IV