Table 2.
Univariate analysis of risk factors for deterioration to AKI stage 3 in SICH patients complicated with AKI
| Characteristics | OR | 95%CI | P value |
|---|---|---|---|
| Demographics | |||
| Age ≥ 65 years | 1.081 | 0.714–1.637 | 0.712 |
| Male | 1.206 | 0.790–1.840 | 0.385 |
| Medical history | |||
| Diabetes | 1.546 | 0.951–2.512 | 0.079 |
| Hypertension | 1.135 | 0.762–1.691 | 0.532 |
| ICU admission | 1.589 | 1.034–2.470 | 0.035 |
| Mechanical ventilation | 2.540 | 1.649–3.911 | <0.001 |
| Medication used | |||
| Mannitol | 1.025 | 0.661–1.591 | 0.912 |
| NSAID | 1.057 | 0.701–1.591 | 0.791 |
| Colloids | 2.186 | 1.377–3.472 | 0.001 |
| Vasoactive drugs | 1.703 | 1.109–2.611 | 0.015 |
| Diuretics | 3.694 | 2.136–6.389 | <0.001 |
| Aminoglycosides | 1.228 | 0.694–2.171 | 0.48 |
| Laboratory data | |||
| Serum sodium (normal) | 0.214 | <0.001 | |
| Hypernatronemia* | 1.719 | 1.101–2.685 | 0.017 |
| Hypernatronemia† | 2.42 | 1.186–4.936 | 0.015 |
| Hypernatronemia‡ | 8.061 | 3.615–17.971 | <0.001 |
| Hyperchloremia | 1.994 | 1.340–2.996 | 0.001 |
| Metabolic acidosis | 2.186 | 1.447–3.301 | <0.001 |
| Hypoproteinemia | 1.028 | 0.689–1.534 | 0.893 |
| Elevated serum creatine kinase | 2.962 | 1.981–4.428 | <0.001 |
| Hyperuricemia | 3.074 | 1.990–4.748 | <0.001 |
| Elevated white blood cell count | 1.716 | 1.107–2.662 | 0.016 |
| Anemia | 1.637 | 1.081–2.478 | 0.02 |
| Proteinuria | 1.82 | 1.505–2.200 | <0.001 |
| Hematuresis | 1.406 | 1.219–1.662 | <0.001 |
ICU admission intensive care unit admission;Serum sodium (normal): serum sodium concentration ≤ 145 mmol/L; Hypernatronemia*: serum sodium concentration > 145 mmol/L & ≤ 160 mmol/L; Hypernatronemia†: serum sodium concentration > 160 mmol/L & ≤ 170 mmol/L; Hypernatronemia‡: serum sodium concentration > 170 mmol/L.