Table 2.

Pharmacokinetic parameters of cannabidiolic acid (CBDA) following oral administration of industrial hemp to achieve a 5.4 mg/kg dose (n = 8).

Parameter	Unit	Geometric mean	Median	Range
λz	1/h	0.05	0.05	0.04–0.07
T1/2	h	14.1	13.89	9.62–19.59
Tmax	h	11.82	10	6.0–24.0
Cmax	ng/mL	72.7	74.7	36.5–177.0
AUC0-∞	h × ng/mL	2718.6	2995.8	1217.7–5714.6
AUC0-last	h × ng/mL	2593.9	2772.2	1099.7–5698.6
AUC extrapolated	%	3.0	3.1	0.3–11.2
AUMC0-∞	h2 × ng/mL	83,289.8	91,850	44,793.2–156,711.1
MRT0-∞	h	30.6	29.5	25.8–37.6
MRT0-last	h	27.6	27.0	23.4–32.1
Cl/F	mL/h/kg	1958.3	1955.0	927.5–4023.8
Vz/F	L/kg	39.7	42.3	12.9–107.2