Table 1.
Participant characteristics.
| Characteristics | CD | NFA | P value |
|---|---|---|---|
| Number of subjects (male/female) | 101 (17/84) | 95 (19/76) | 0.567 |
| Macroadenomas (n) | 10 | 0 | |
| Microadenomas (n) | 91 | 95 | |
| Mean age (year) | 37.4 ± 12.6 | 35.4 ± 11.5 | 0.215 |
| Years of education | 12.2 ± 5.7 | 13.1 ± 6.6 | 0.683 |
| Education level | 0.848 | ||
| Low (n/%) | 44 (43.5%) | 40 (42.1%) | |
| Medium (n/%) | 41 (40.6%) | 37 (38.9%) | |
| High (n/%) | 16 (15.8%) | 18 (18.9%) | |
| Smoking history (n) | 3 (2.9%) | 2 (2.1%) | |
| Drinking history (n) | 6 (5.9%) | 4 (4.2%) | |
| Disease course (year) | 3.9 ± 3.4 | – | |
| Waist circumference (cm) | 91.8 ± 10.1 | 80.2 ± 8.6 | < 0.01 |
| BMI (kg/m2) | 25.0 ± 3.5 | 21.6 ± 2.7 | < 0.01 |
| Total cholesterol (mmol/l) | 5.4 ± 1.2 | 4.3 ± 1.1 | < 0.05 |
| Triglycerides (mmol/l) | 1.6 ± 1.0 | 1.4 ± 0.7 | < 0.05 |
| HbA1c (%) | 6.3 ± 1.2 | 5.6 ± 0.4 | < 0.05 |
| Fasting serum glucose (mmol/l) | 5.9 ± 2.1 | 5.1 ± 1.8 | 0.117 |
| Systolic blood pressure (mm/Hg) | 147.0 ± 21.7 | 114 ± 16.5 | < 0.01 |
| Diastolic blood pressure (mm/Hg) | 97.5 ± 15.3 | 82 ± 6.9 | < 0.01 |
| Pre-diabetes (%) | 15.8% | 2.1% | < 0.01 |
| Diabetes (%) | 45.5% | 4.2% | < 0.01 |
| Hypertension (%) | 77.2% | 2.1% | < 0.01 |
| Hypothyroidism (%) | 26.7% | 0 | |
| Hypogonadism (%) | 36.6% | 0 |