Table 3.

Study design of the available publications included in the meta-analysis (up to March 31, 2020).

	Our study	Codoñer et al.20	Tan et al.29	Hidalgo-Cantabrana et al.37	Chen et al.30	Huang et al.6	Scher et al.32	Shapiro et al.38
Publication year		2018	2018	2019	2018	2018	2015	2019
Population	Caucasian/Argentine	Caucasian/Spain	Asian/China	Caucasian/Spain	Asian/China	Asian/China	Caucasian/US	Caucasian/Israel
Psoriasis patients (n)	55	52	14	19	35	32	15 Ps / 16 PsA	24
Non-Psoriasis controls (n)	27	300 (from HMP)	14	20	27	64	17	22
Plaque psoriasis exclusive	yes	yes	yes	yes	yes	no	NA	NA
Matchead by	Age, sex & BMI	No	No	Age	Age, sex & BMI	No	Age & sex	Age, sex & comorbidities
Active systemic treatment	No	No	NA	No	Yes	Yes	No	Yes
Stratified by severity	Yes	No	No	No	NA	Yes	No	No
Concomitant PsA	no	NA	NA	NA	yes	no	yes	NA
16S region analyzed	V3–V4	V3–V4	V4	V2–V3	V3–V4	V4–V5	V1–V2	V4
Platform	Illumina	Illumina	Illumina	Ion Chef	Illumina	Illumina	Illumina	Illumina
Average reads	152,939	~ 85,000	~ 30,000	233,113	~ 85,000	NA	NA	~ 50,000
Raw data available at	PRJNA574485	Avaiable upon request to the corresponding author	NA	PRJNA517056	PRJNA379878	NA	NA	NA