Table 2.

ROC analyses of PET/CT parameters for predicting survival outcomes.

Variable	Median (range)	Event			Death
		AUC	Cut-off	P	AUC	Cut-off	P
Total population (n = 50)
Colon lesion
SUVmax	23.4 (19.4–28.2)	0.652	14.5	0.105	0.725	15.7	0.014
MTV	47.8 (16.7–137.0)	0.568	70.0	0.457	0.512	180.0	0.905
TLG	585.4 (176.8–1919.2)	0.518	2,165.2	0.847	0.580	2,165.2	0.380
Non-colon lesion
SUVmax	11.8 (1.0–22.0)	0.703	7.8	0.008	0.610	1.0	0.210
MTV	7.1 (0–62.3)	0.867	56.5	0.001	0.810	62.3	0.001
TLG	49.3 (0–713.4)	0.863	636.1	0.001	0.794	830.2	0.001
Total lesion
SUVmax	23.8 (19.4–29.7)	0.602	16.2	0.314	0.663	16.2	0.145
MTV	90.5 (26.7–221.6)	0.782	80.0	0.001	0.748	80.0	0.010
TLG	1,236.5 (425.3–2,972.9)	0.715	1,288.7	0.007	0.661	1,288.7	0.091
Colon lesion-dominant subgroup (n = 35)
Colon lesion
SUVmax	24.3 (20.8–30.3)	0.637	14.5	0.347	0.786	14.5	0.108
MTV	48.6 (17.7–144.8)	0.640	70.0	0.293	0.510	70.0	0.950
TLG	974.0 (220.5–2,662.7)	0.567	176.8	0.594	0.604	1,285.2	0.368
Non-colon lesion
SUVmax	7.4 (1.0–18.5)	0.707	1.0	0.039	0.542	1.0	0.658
MTV	1.6 (0–9.4)	0.813	1.6	0.001	0.668	1.6	0.049
TLG	7.1 (0–65.4)	0.793	7.1	0.001	0.625	7.1	0.149
Total lesion
SUVmax	24.3 (20.8–30.3)	0.630	14.5	0.379	0.786	14.5	0.108
MTV	56.0 (19.4–166.8)	0.680	73.05	0.188	0.510	73.05	0.950
TLG	1,022.1 (228.1–2,866.3)	0.587	176.8	0.511	0.604	1,311.9	0.368

ROC, Receiver operating characteristics; AUC, Area under the curve; SUVmax, Maximum standard uptake value; MTV, Metabolic tumor volume; TLG, Total lesion glycolysis; Non-colon lesion SUVmax was assigned a value of 1.0 if there was no detectable lesion on PET/CT.