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. 2020 Jul 30;21:151. doi: 10.1186/s13059-020-01979-4

Table 1.

Features used by RADAR

Category Feature Source Scoring scheme
Universal Cross-population conservation eCLIP Adjusted entropy
Cross-species conservation GERP Sigmoid function
Structural conservation Evofold Fixed value
RBP Binding hub eCLIP Adjusted entropy
RBP-gene association shRNA RNA-Seq Fixed value
Motif disruption Bind-n-Seq Adjusted entropy
DREME
User-specific RBP regulatory potential Expression Fixed value
Differentially expressed genes Prior knowledge Fixed value
Mutation recurrence Mutation profiles Fixed value