. 2020 Jul 30;19:32. doi: 10.1186/s12941-020-00375-x

Table 5.

Characteristics of 44 well-described patients with peritonsillar abscess (PTA) and descending mediastinitis (DM)

References	Age (years)	Gender	Microbiologic findings	Treatment of PTA prior to DM development		Outcome
References	Age (years)	Gender	Microbiologic findings	Surgery	Antibiotics	Outcome
Zgheib [89]	52	M	Group A streptococci, E. corrodens	Drain	Ery → Clinda	Survived
Civen [74]	45	M	C. diversus, Group F streptococci, VGS, CNS, P. bucca, P. intermedia, F. nucleatum, A. odontolyticus, B. dentium, L. catenaforme, P. anaerobius, P. asaccharolyticus	Simultaneous^a		Survived
Alsoub [75]	32	M	VGS	Incision	Cephalothin	Survived
Alsoub [75]	47	M	Negative cultures	Incision	Cephalothin	Survived
Cordero [88]	27	M	S. anginosus, anaerobes	Incision	None	Survived
Nielsen [91]	25	M	S. anginosus, Bacteroides spp.	Acute tons	Iv. pen + metro	Survived
Endo [93]	67	M	Peptostreptococcus sp., C. albicans, Gram-positive coccus	Simultaneous^a		Survived
Endo [93]	63	F	Gram-positive coccus + Gram-positive rod + Gram-negative rod	Simultaneous^a		Survived
Manecke [96]	29	M	Beta-hemolytic streptococci, Pepto-streptococcus spp., Bacteroides spp.	Simultaneous^a		Survived
Corsten [99]	71	M	Gram-positive bacilli	No	Clinda	Survived
Sancho [76]	19	F	A. coloaceticus, P. aeruginosa, B. fragilis	NI^b		Survived
Sancho [76]	71	M	S. aureus, E. cloacae, B. fragilis	NI^b		Died
Sancho [76]	39	M	S. aureus, P. aeruginosa, B. fragilis	NI^b		Survived
Laxmipathi [90]	70	M	S. aureus	Drain	NI	Survived
Asrar [97]	36	M	Non-hemolytic streptococci	Incision	Iv. Unspec	Survived
Lautermann [77]	52	NI	AHS, CNS	Simultaneous^a		Survived
Lautermann [77]	61	NI	Negative cultures	Simultaneous^a		Survived
Mihos [78]	26	M	S. hominis, Fusobacterium spp.	Drain	Unspec	Survived
Collin [79]	48	M	S. salivarius	Incision	Amox-clav + metro	Survived
Sandner [80]	26	M	AHS, N. catarrhalis, C. albicans	Simultaneous¹		Survived
Sandner [80]	45	M	AHS, VGS, S. aureus, S. marcescens	Drain	Unspec	Died
Roccia [68]	65	M	S. anginosus	NI^b		Survived
Roccia [68]	50	M	S. epidermidis, B. melaninogenicus	NI^b		Died
Roccia [68]	53	M	Negative cultures	NI^b		Died
Roccia [68]	20	M	S. aureus	NI^b		Survived
Roccia [68]	37	F	S. aureus	NI^b		Survived
Roccia [68]	16	F	S. anginosus	NI^b		Survived
Roccia [68]	58	M	S. aureus, A. fumigatus	NI^b		Survived
Roccia [68]	52	M	VGS, Prevotella oralis	NI^b		Died
Roccia [68]	33	F	H. influenzae	NI^b		Survived
Roccia [68]	65	M	S. aureus	NI^b		Survived
Roccia [68]	66	M	S. epidermidis, P. aeruginosa	NI^b		Survived
Roccia [68]	57	M	S. haemolyticus, B. cepacia	NI^b		Died
Roccia [68]	58	F	S. aureus	NI^b		Survived
Roccia [68]	53	M	VGS, P. aeruginosa	NI^b		Survived
Kinzer [81]	67	NI	S. intermedius, Bacteroides spp.	Simultaneous^a		Died
De Freitas [83]	18	F	NI	Simultaneous^a		Survived
De Freitas [83]	30	F	NI	Incision	Unspec	Survived
Nakamura [100]	77	F	Bacteroides spp., Corynebacterium spp.	Simultaneous^a		Survived
Anderson [102]	NI	F	VGS	Simultaneous^a		Survived
Iyer [94]	74	M	Gram-positive, Gram-negative, anaerobes	Simultaneous^a		Survived
Gallo [98]	57	M	S. aureus (MR)	NI^b		Survived
Wahab [95]	29	F	Negative cultures	Asp	Pen + metro → clari + metro	Survived
Geerts [82]	34	M	S. aureus, S. salivarius, F. necrophorum	Simultaneous^a		Survived

Bacterial names are written as reported by author (and not changed according to current nomenclature)

M male, F female, Drain drainage, Ery erythromycin, → changed to, Clinda clindamycin, VGS Viridans group streptococci, CNS Coagulase-negative staphylococci, Tons tonsillectomy, Iv intraveneous, Pen penicillin, Metro metronidazole, NI no information, Unspec unspecified, AHS alpha-hemolytic streptococci, Amox-clav amoxicillin-clavulanate, MR Methicillin resistant, Asp: aspiration, Clari clarithromycin

^aSimultaneous diagnosis and treatment of PTA and DM

^bNo information regarding the time relation between PTA and DM