Table 3.
Univariate and multivariate analysis of the correlation of radiotherapy and chemotherapy with OS among high ABCC8 mRNA expression glioma patients in CGGA. CI = confidence interval; HR = hazard ratio.
| Variable | Univariate cox regression | Multivariate cox regression | ||||
|---|---|---|---|---|---|---|
| p value | HR | 95% CI (lower–upper) | p value | HR | 95% CI (lower–upper) | |
| Gender | 0.014 | 1.533 | 1.092–2.152 | 0.161 | 1.320 | 0.895–1.946 |
| Age | 0.000 | 2.023 | 1.438–2.845 | 0.001 | 1.991 | 1.329–2.983 |
| Histopathology | 0.000 | 1.975 | 1.654–2.359 | 0.645 | 1.072 | 0.798–1.438 |
| WHO grade | 0.000 | 2.898 | 2.269–3.701 | 0.000 | 2.429 | 1.735–3.402 |
| IDH mutant | 0.000 | 0.294 | 0.206–0.420 | 0.000 | 0.427 | 0.274–0.664 |
| 1p/19q codel | 0.000 | 0.322 | 0.216–0.481 | 0.179 | 0.640 | 0.334–1.226 |
| Radiotherapy | 0.195 | 1.299 | 0.875–1.928 | 0.809 | 1.059 | 0.664–1.691 |
| Chemotherapy | 0.533 | 1.125 | 0.777–1.628 | 0.008 | 0.526 | 0.326–0.848 |