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. 2020 Jul 29;10:12728. doi: 10.1038/s41598-020-69026-7

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Positive enriched map for Cluster A. Each black circle (node) represents a pathway, circle size represents the number of genes represented between the gene sets and data. Links between pathways were established when 2 pathways had a Jaccard index > 0.4, given the expressed genes. Colour squares denote a category that comprises several collections (yellow circles) with shared biological function. The embedded table shows the number of pathways enriched in each collection. All the enriched pathways had an FDR < 0.05 and a p value < 0.01.