Table 3.

Summary of Glasgow Royal Infirmary studies

Study	Year	Patient no.	Years incl.	Additional incl. & excl. criteria	Inflammatory marker	Measurement intervals	Minimum follow-up
McMillan et al [10]	2003	174	1993–1998	Curative resection of CRC, staged by Dukes	CRP	Preoperative 4 mo postoperative	Unclear
Canna et al [33]	2005	147	1997–2001	Curative resection of Dukes B or C CRC	CRP	Preoperative	30 mo
Carruthers et al [38]				T3 and T4 borderline or unresectable rectal cancer having preoperative chemoradiotherapy.	NLR, PLR, albumin, CEA	Preradiotherapy	0.5 mo
Crozier et al [34]	2007	180	1999–2004	Curative resection of CRC. Excludes any emergency cases, preoperative radiotherapy, clinical infection, and inflammatory conditions	CRP	Preoperative Day 2 postoperative	22 mo
Crozier et al [35]	2009	188	1999–2006	Curative resection of CRC, preoperative CRP and albumin available	mGPS	Preoperative	12 mo
Roxburgh et al [12]	2009	287	1997–2004	Curative resection of CRC. Excludes emergency presentation, infection, chronic inflammatory conditions, preoperative radiotherapy	GPS	Preoperative	34 mo
Proctor et al [36]	2011	27,031	2000–2007	Patients with any cancer, as identified in the Scottish Cancer Registry that had blood tests recorded any time before diagnosis	CRP, albumin, white cell count (WCC), neutrophils, LMR, PLR, mGPS, NLR, PI	Variable	Unclear
Richards et al [37]	2012	343	1997–2007	Stage I–III CRC	mGPS	Preoperative	45 mo