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. 2019 Nov 8;1(2):49–55. doi: 10.1016/j.sopen.2019.08.002

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© 2019 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig 6 — Stem cell–like/tumor-initiating cell–like features of CTC in pancreatic cancer:

A, Circulating tumor cells from pancreatic cancer patients demonstrating (A) pan-cytokeratin–positive, ALDH-positive CTC (merge); (B) DAPI (blue); (C) aldehyde dehydrogenase (green); and (D) pan-cytokeratin (red).

B, Circulating tumor cells from pancreatic cancer patients demonstrating (A) pan-cytokeratin–positive, CD133-positive, CD44-positive CTC (merge); (B) DAPI (blue); (C) CD133 (green); (D) pan-cytokeratin (red); and (E) CD44 (pink).

C, Circulating tumor cells from pancreatic cancer patients demonstrating (A) pan-cytokeratin–positive, CD133-positive, CD44-negative CTC (merge); (B) DAPI (blue); (C) CD133 (green); (D) pan-cytokeratin (red); and (E) CD44 negativity (absence of pink).

Printed with permission.