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. Author manuscript; available in PMC: 2021 Jun 1.
Published in final edited form as: J Nucl Cardiol. 2019 Dec 3;27(6):2083–2099. doi: 10.1007/s12350-019-01973-9

Figure 4.

Figure 4.

Post-mortem images of the left ventricle in a canine model. Hybrid PET/MRI after constant simultaneous infusion of FDG and Gd-DTPA in a large animal model of inflammation post-MI. Registration is “Perfect” as the PET/MRI were acquired post-euthanasia. Arrows indicate center of infarct (blue) and edges of infarct (orange). Notice that inflammation by PET extends beyond the infarct into the “remote” left ventricular myocardium but is not transmural in this “remote” region. Uptake of FDG in the “remote” myocardial tissue PET images could be further improved by MRI-guided partial volume correction. Suppression was achieved through lipid infusion, heparin injection, and fasting.