Table 3.
LncRNAs as diagnostic biomarkers in gastric cancer
| Clinical application | LncRNA | Expression | Diagnosis accuracy | Reference |
|---|---|---|---|---|
| Diagnostic biomarker |
H19 | up | AUC was 0.838; p<0.001; sensitivity, 82.9%; specificity, 72.9% | 171 |
| FAM49B-AS, GUSBP11 and CTDHUT | up | The combined area under curve of these lncRNAs was 0.818 | 172 | |
| lnc-GNAQ-6:1 | down | AUC was 0.732 | 175 | |
| UCA1 | up | AUC was 0.759; The sensitivity and specificity were 93.20% and 78.63% | 176 | |
| B3GALT5-AS1 | up | AUC was 0.816 | 177 | |
| HOTAIR | up | AUC was 0.8416; The sensitivity and specificity were 66.67 and 87.04% | 178 | |
| lncUEGC1 | up | AUC was 0.8406 | 179 | |
| PANDAR, FOXD2-AS1, and SMARCC2 | up | The AUC of the combinative diagnostic value of these three lncRNAs was 0.839 | 180 | |
| TINCR, CCAT2, AOC4P, BANCR, and LINC00857 | up | The AUC of the combinative diagnostic value of these five lncRNAs was 0.91 | 181 |