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. 2020 Jul 9;10(19):8513–8527. doi: 10.7150/thno.47243

Figure 7.

Figure 7

PMI-Au SNH was efficacious by intravenous or intragastrical administration. (A) Ex vivo fluorescent images of tumors and major organs from Cy3PMI-Au SNH mice after 4h tail vein injection (iv) or oral gavage (ig). (B) Tumor growth curves in nude mice bearing HCT116 tumor with intravenous administration (n =5/group). (C-D) Photo (C) and weights (D) of the tumors excised at the end of the experiment. (E) H&E staining (×200) of HCT116 solid tumor tissues after 12-day treatments. (F) representative images of Tunel staining for tumor tissue taken by confocal laser scanning micrscope (CLSM) (scale bar: 60 µm). (G) Tumor growth curves in nude mice bearing HCT116 tumor with intragastrical administration (n =5/group). (H, I) Photo (C) and weights (D) of the tumors excised at the end of the experiment. (J) H&E staining (×200) of HCT116 solid tumor tissues after 12-day treatments. (K) representative images of Tunel staining for tumor tissue taken by confocal laser scanning micrscope (CLSM) (scale bar: 60 µm).