Table 3.

Results of quantitative analyses of dynamic PET data. Mean (± sd) values for Patlak K_i (K_i_P) [mL/cm³/min], SA K1 (K1_SA) [mL/cm³/min], SA K_i (K_i_SA) [mL/cm³/min], Logan V_t (V_t_L) [mL/cm³] and the compartmental model K_i (K_i_CM) [mL/cm³/min] in primary tumor and healthy lung. A double input SA was used to investigate the volumes of distribution of the parent and of the metabolite in the lesions. V_{T_par} and V_{T_metab} are the volumes of distribution for the parent and the metabolite, respectively. Parent and metabolite both contribute to the final PET signal.

			Single Input SA		Double Input SA
Region	Ki_P	Vt_L	Ki_SA	K1_SA	VT_par	VT_metab	Ki_SA
Primary tumor	0.05 (±0.04)	6.38 (±7.56)	8E-05 (±9E-05)	0.26 (±0.31)	0.99 (±0.70)	0.37 (±0.63)	8.75E-05 (±1E-04)
Healthy lung	0.0 2 (±0.22)	2.87 (±2.32)	4E-05 (±5E-05)	0.07 (±0.99)