Table 1.
The prediagnostic serum piR-54265 levels (copy number per μL) were associated with future CRC diagnosis
| N | Median level (IQR)a | Pb | OR (95% CI)c | OR (95% CI) per S.D.d | |
|---|---|---|---|---|---|
| Controls | 614 | 1208.0 (662.3, 1514.0) | Reference | Reference | Reference |
| Cases | 307 | 1453.3 (1108.4, 2086.9) | 2.13e-12 | 2.10 (1.66, 2.65) | 1.69 (1.43, 1.99) |
| Diagnosed at 0 year | 79 | 1635.7 (1230.9, 2629.0) | 1.77e-12 | 7.23 (4.00, 13.08) | 3.98 (2.63, 6.02) |
| Diagnosed at 1 year | 53 | 1509.7 (1129.1, 2439.9) | 7.66e-05 | 2.80 (1.60, 4.89) | 2.06 (1.39, 3.06) |
| Diagnosed at 2 years | 66 | 1489.3 (1114.6, 1900.5) | 2.24e-04 | 2.45 (1.49, 4.03) | 1.86 (1.32, 2.62) |
| Diagnosed at 3 years | 109 | 1309.5 (748.2, 1715.6) | 4.62e-02 | 1.24 (0.90, 1.72) | 1.16 (0.93, 1.45) |
a: IQR, inter-quartile range. b: Mann-Whitney U test. c: Comparison of the forth quartile to the first quartile (Reference) for the serum piR-54265 level. Data were computed with logistic regression models and adjusted for BMI, smoking and alcohol drinking status. d: Per S.D. increased in the serum piR-54265 level.