Table 1.
Clinical character | OS (months) | |||
---|---|---|---|---|
Univariate analysis | Multivariatie analysis | |||
HR (95% CI) | P value* | HR (95% CI) | P value* | |
Age (>50y vs. ≤ 50) | 1.092 (0.620-1.924) | 0.761 | 1.032 (0.548-1.945) | 0.921 |
Gender (Female vs. Male) | 1.715 (0.770-3.820) | 0.187 | 2.523 (0.94606.730) | 0.064 |
Cirrhosis (yes vs. no) | 0.823 (0.369-1.837) | 0.635 | 0.369 (0.129-1.055) | 0.063 |
Histological Grade (G1-2,G2 vs. G2-3,G3) | 0.957 (0.526-1.740) | 0.886 | 0.617 (0.318-1.196) | 0.153 |
TNM stage (I vs. II) | 1.627 (0.926-2.858) | 0.09 | 0.986 (0.325-2.987) | 0.980 |
Tumor size (≤ 3 cm vs. > 3 cm) | 2.273 (1.159-4.457) | 0.017 | 3.690 (1.601-8.503) | 0.002 |
Tumor number (≤ 3 n vs. > 3 n) | 1.504 (0.767-2.947) | 0.235 | 0.971 (0.471-2.005) | 0.938 |
AFP (<400 μg/L vs. 400 μg/L) | 1.790 (1.017-3.151) | 0.044 | 0.569 (0.277-1.168) | 0.124 |
Cirrhosis Nodule size (≤ 3 mm vs. > 3mm) | 1.093 (0.622-1.920) | 0.757 | 0.691 (0.356-1.341) | 0.274 |
Clinical stage (I vs. II) | 1.888 (1.069-3.337) | 0.029 | 1.006 (0.336-3.016) | 0.992 |
Recurrence (yes vs. no) | 6.461 (2.884-14.473) | 0.000 | 9.474 (3.680-24.392) | 0.000 |
ZFP91 | 0.256 (0.127-0.515) | 0.000 | 0.320 (0.149-0.689) | 0.004 |
*Cox multivariate proportional hazard model.