Table 3.
Weights of mice and organs, mortality, and in vivo pathogenicity in animals challenged with eight C. albicans isolates to form oral and systemic infections
| No. |
Mouse weight change (g)
mean (range) |
Organ weight (g)
mean (range) |
Mortality
(day) |
In vivo
pathogenicity (Log CFU/g tissue) (median) range
|
||||
|---|---|---|---|---|---|---|---|---|
| Systemic | Oral | Systemic | Oral | Systemic | Oral | Systemic | Oral | |
| 93-62 | -3.9 ((-5.2)-(-2.4)) |
- 4.0 ((-5.3)-(-2.6)) |
0.21 (0.14- 0.30) |
0.07 (0.04- 0.09) |
2/7 (5) | 0/7(0) | (4.43) 3.69- 4.73 |
(4.41) 2.95- 5.26 |
| 93-1428 | -1.5 ((-2.5)-(-0.7)) |
-4.2 ((-5.5)-(-2.8)) |
0.20 (0.12- 0.28) |
0.07 (0.05- 0.10) |
0/7 (0) | 1/7(2) | (1.75) 1.03- 2.78 |
(4.73) 4.59- 4.82 |
| 93-107 | -1.0 ((-2.3)-(-0.2)) |
-3.8 ((-5.6)-(-0.5)) |
0.18 (0.14- 0.20) |
0.07 (0.04- 0.09) |
1/7 (7) | 0/7(0) | (2.67) 1.46- 4.33 |
(4.22) 3.87- 4.55 |
| 93-1878 | -5.1 ((-7.2)-(-2.6)) |
-4.2 ((-5.2)-(-3.1)) |
0.20 (0.16- 0.24) |
0.07 (0.05- 0.10) |
0/7 (0) | 0/7(0) | (3.37) 2.39- 4.35 |
(4.72) 4.30- 5.27 |
| 93-2553 | -3.9 ((-6.0)-(-0.3)) |
-4.5 ((-5.5)-(-3.5)) |
0.19 (0.18- 0.22) |
0.07 (0.05- 0.09) |
1/7 (5) | 0/7(0) | (3.89) 3.23- 4.44 |
(5.11) 4.13- 5.68 |
| 93-2381 | -2.5 ((-4.3)-(-0.7)) |
-4.1 ((-5.2)-(-2.8)) |
0.19 (0.14- 0.22) |
0.08 (0.03- 0.11) |
0/7 (0) | 1/7(2) | (3.68) 1.93- 4.97 |
(4.81) 4.38- 5.19 |
| 93-1471 | -5.2 ((-8.7)-(-3.3)) |
-4.0 ((-5.3)-(-2.9) |
0.20 (0.14- 0..21) |
0.09 (0.07- 0.11) |
0/7 (0) | 0/7(0) | (3.59) 2.75- 4.79 |
(4.64) 4.32- 5.29 |
| 93-1095 | -4.4 ((-4.8)-(-3.5)) |
-4.5 ((-5.3)-(-2.8)) |
0.19 (0.17- 0.21) |
0.09 (0.07- 0.10) |
1/7 (5) | 0/7(0) | (3.75) 2.48- 5.28 |
(5.19) 4.98- 5.54 |