Figure 3.
White cell count corrected cAMP concentrations and LPS-induced cytokine responses in preterm infant peripheral blood (Day 1 and 7 of life) are associated with exposure to choriamnionitis. Medians and 95% CI are depicted for A) cAMP, B) TNF-α, C) IL-12p70, D) IL-6, E) IL-10 and F) IL-1β. ****, P<0.001; **, P<0.01; *, P<0.05 comparing infants exposed to histiological chorioamnionitis (HCA+) to those unexposed (HCA-) by Mann-Whitney test. n=12–16/group for cord samples and 39–44 per group for peripheral blood samples.