Table 2.
Spearman rank correlations of cord and peripheral blood (preterm and term) lysate cAMP concentrations versus absolute white cell counts.
| Cell type | Blood sample | Median and range (109 cells/L) | r (95% CI: lower, upper) | p-value (n) |
|---|---|---|---|---|
| WBC | Cord | 4.51 (0.96–16.4) | 0.43 (0.15, 0.64) | 0.001 (47) |
| DOL1 | 6.00 (1.6–47.0) | 0.24 (0.06, 0.40) | 0.004 (124) | |
| DOL7 | 6.57 (1.0–25.0) | 0.45 (0.27, 0.60) | <0.0001 (95) | |
| DOL14 | 6.19 (2.9–26.4) | −0.06 (−0.26, 0.15) | 0.29 (95) | |
| DOL21 | 5.73 (2.1–16.6) | 0.06 (−0.16, 0.26) | 0.30 (89) | |
| DOL28 | 5.86 (1.9–13.1) | 0.03 (−0.16, 0.21) | 0.38 (113) | |
| PMN | Cord | 1.47 (0.006–9.0) | 0.45 (0.18, 0.66) | 0.0007 (47) |
| DOL1 | 2.41 (0.006–15.5) | 0.18 (0.001, 0.35) | 0.02 (124) | |
| DOL7 | 2.15 (0.03–19.8) | 0.41 (0.22, 0.57) | <0.0001 (95) | |
| DOL14 | 2.44 (0.01–19.8) | 0.04 (−0.17, 0.24) | 0.36 (96) | |
| DOL21 | 1.69 (0.01–10.2) | −0.04 (−0.25, 0.18) | 0.37 (89) | |
| DOL28 | 1.46 (0.002–8.6) | 0.03 (−0.16, 0.22) | 0.39 (113) | |
| Classical Monocytes | Cord | 0.24 (0.001–1.2) | 0.3 (0.006, 0.55) | 0.02 (47) |
| DOL1 | 0.05 (0.002–0.38) | 0.08 (−0.10, 0.26) | 0.18 (124) | |
| DOL7 | 0.60 (0.0001–1.6) | 0.30 (0.10, 0.48) | 0.002 (94) | |
| DOL14 | 0.59 (0.0002–1.7) | 0.09 (−0.12, 0.29) | 0.19 (96) | |
| DOL21 | 0.45 (0.0005–1.9) | 0.21 (−0.003, 0.40) | 0.02 (89) | |
| DOL28 | 0.47 (0.0002–0.3) | 0.11 (−0.08, 0.29) | 0.11 (113) | |
| CD16+Monocytes | Cord | 0.04 (0.004–0.2) | 0.14 (−0.16, 0.42) | 0.17 (47) |
| DOL1 | 0.44 (0.0004–26.1) | 0.25 (0.08, 0.41) | 0.002 (124) | |
| DOL7 | 0.06 (0.0009–0.3) | 0.21 (0.003, 0.40) | 0.02 (94) | |
| DOL14 | 0.08 (0.001–0.4) | 0.14 (−0.06, 0.33) | 0.08 (96) | |
| DOL21 | 0.08 (0.008–0.4) | 0.14 (−0.07, 0.34) | 0.10 (89) | |
| DOL28 | 0.08 (0.02–0.3) | 0.12 (−0.07–0.29) | 0.11 (113) | |
| T cells | Cord | 0.88 (0.3–2.9) | 0.21 (−0.08, 0.47) | 0.07 (47) |
| DOL1 | 0.96 (0.17–5.8) | −0.04 (−0.22, 0.14) | 0.34 (124) | |
| DOL7 | 1.37 (0.24–5.2) | 0.15 (−0.06, 0.34) | 0.08 (95) | |
| DOL14 | 1.38 (0.07–6.6) | −0.22 (−0.41, −0.02) | 0.01 (96) | |
| DOL21 | 1.54 (0.2–5.7) | −0.06 (−0.27, 0.15) | 0.28 (89) | |
| DOL28 | 1.64 (0.23–4.6) | 0.03 (−0.16, 0.22) | 0.38 (113) | |
| B cells | Cord | 2.28 (0.005–1.6) | 0.26 (−0.03, 0.51) | 0.04 (47) |
| DOL1 | 2.08 (0.0006–1.1) | 0.05 (−0.13, 0.24) | 0.27 (124) | |
| DOL7 | 0.23 (0.002–1.1) | 0.38 (0.18, 0.54) | <0.0001 (95) | |
| DOL14 | 0.27 (0.002–11.0) | 0.08 (−0.12, 0.28) | 0.22 (96) | |
| DOL21 | 0.30 (0.0005–0.9) | 0.07 (−0.15, 0.27) | 0.27 (89) | |
| DOL28 | 0.34 (0.0006–1.3) | 0.04 (−0.15, 0.23) | 0.34 (113) |
WBC, White blood cells.