Table 3a.

Significant spearman rank correlations of cAMP concentrations and LPS-stimulated cytokine concentrations (all WCC-corrected).

Infant Group	Cytokine	Sample (DOL)	r (95% CI; lower, upper limit)	n	p-value
Preterm	TNF-α	7	0.35 (0.16 to 0.52)	96	0.0002
		14	0.32 (0.12 to 0.49)	95	0.0009
		21	0.35 (0.15 to 0.53)	89	0.0004
		28	0.41 (0.23 to 0.56)	102	<0.0001
	IL-1b	7	0.28 (0.08 to 0.46)	96	0.003
		14	0.31 (0.12 to 0.49)	95	0.0009
		21	0.28 (0.07 to 0.46)	89	0.004
		28	0.35 (0.16 to 0.52)	102	0.0001
	IL-6	7	0.35 (0.16 to 0.52)	96	0.0002
		14	0.39 (0.20 to 0.55)	95	<0.0001
		21	0.39 (0.19 to 0.56)	89	<0.0001
		28	0.43 (0.25 to 0.58)	102	<0.0001
	IL-10	Cord	0.38 (0.03 to 0.65)	32	0.02
		7	0.18 (−0.03 to 0.37)	96	0.04
		14	0.31 (0.11 to 0.49)	95	0.001
		21	0.32 (0.12 to 0.50)	89	0.001
		28	0.46 (0.28 to 0.60)	102	<0.0001
	IL-12p70	1	0.19 (−0.003 to 0.37)	108	0.02
		7	0.19 (−0.01 to 0.38)	96	0.03
		14	0.21 (0.002 to 0.40)	95	0.02
		28	0.27 (0.08 to 0.45)	102	0.003
Term	TNF-α	Cord	−0.53 (−0.82 to –0.006)	15	0.02
	IL-10	1	0.50 (−0.03 to 0.81)	15	0.03