REAGENT or RESOURCE	SOURCE	IDENTIFIER
Antibodies
anti-CD66b-Pacific blue	BioLegend	CAT#: 305112
APC-Cy7 Mouse Anti-Human CD16	BD Biosciences	CAT#557758; RRID:AB_396853
CD56 PE-Cy7 Mouse Anti-Human CD56	BD Biosciences	CAT#557747
PE MIP-1b Mouse anti-Human	BD Biosciences	CAT#550078; RRID:AB_393549
Pacific Blue Mouse Anti-Human CD3	BD Biosciences	CAT#558117; RRID:AB_1595437
Anti-Human IgG (Fc specific), highly cross adsorbed-Peroxidase antibody produced in goat	Sigma-Aldrich	CAT#: SAB3701283-1MG
FITC Goat IgG anti-C3	MP Biomedicals	CAT#: 855385
Mouse Anti-Human IgG1-Fc PE	Southern Biotech	CAT # 9054-09
Mouse Anti-Human IgG2-Fc PE	Southern Biotech	CAT # 9060-09
Mouse Anti-Human IgG3-Hinge PE	Southern Biotech	CAT # 9210-09
Mouse Anti-Human IgG4-Fc PE	Southern Biotech	CAT # 9200-09
Mouse Anti-Human IgA1-Fc PE	Southern Biotech	CAT # 9130-09
Mouse Anti-Human IgM-Fc PE	Southern Biotech	CAT # 9020-09
BV605 Mouse Anti-Human CD11b	BD Biosciences	CAT# 562721
Bacterial and Virus Strains
SARS-CoV-2-S pseudovirus with a luciferase reporter	This paper
Chemicals, Peptides, and Recombinant Proteins
SARS-CoV-2 S	Obtained from the lab of Dr. Eric Fischer
SARS-CoV-2 RBD	Obtained from the lab of Dr. Aaron Schmidt
SARS-CoV-2 N	Aalto Bio Reagents	CAT # CK 6404-b
Human Fc receptors	Produced at the Duke HumanVaccine Institute, {Boesch, 2014 #15}
Streptavidin-R-Phycoerythrin	Prozyme	CAT#:PJ31S
FIX&Perm Cell Permeabilization Kit	Life Tech	CAT#: GAS001S100, GAS002S100
Brefeldin A	Sigma Aldrich	CAT#: B7651
GolgiStop	BD Biosciences	CAT#: 554724
Luciferase Assay Reagent	Promega	CAT#: E1483
Critical Commercial Assays
BirA-500: BirA biotin-protein ligase standardreaction kit	Avidity	CAT#: BirA500
RosetteSep Human NK Cell Enrichment Cocktail	Stem Cell Technologies	CAT#: 15065
Steady-Glo Luciferase Assay	Promega	CAT#: E2510
Experimental Models: Cell Lines
THP-1 Cells	ATCC	CAT#: TIB-202; RRID: CVCL_0006
Recombinant DNA
psPAX2	AIDS Reagent	CAT#11348
pLenti-CMV Puro-Luc	Addgene	CAT#17447
pcDNA3.1-SARS CoV-2.SΔCT	This paper
pcDNA3.1(-)-hACE2	Addgene	CAT# 1786
Software and Algorithms
GraphPad Prism	GraphPad	https://www.graphpad.com/scientificsoftware/prism/
Intellicyt ForeCyt Software	Sartorious	https://intellicyt.com/products/software/
Python programming language	Version 3.6.8	https://www.python.org/
Other
FluoSpheres NeutrAvidin-Labeled Microspheres, 1.0 μm, yellow-green fluorescent (505/515), 1% solids	Invitrogen	CAT#: F8776
FluoSpheres NeutrAvidin-Labeled Microspheres, 1.0 μm, red fluorescent (505/515), 1% solids	Invitrogen	CAT#: F8775
MagPlex microspheres	Luminex corporation	CAT#: MC12001-01, MCI12040-01, MCI10077-01