Fig 2. Effects of HFD or control diet on adiposity of mice without Ahr knockout (Cre^neg) or with Pdgfrα-Cre knockout (Pdgfrα-Cre^pos).

A. Adiposity of mice on control diet; B. Adiposity of mice on HFD. Fat mass was assessed using NMR at 14 weeks on HFD or control in mice as described in the Materials and Methods. Cre^neg and Pdgfrα-Cre^pos groups consisted of 7 mice each for HFD and 6 mice each for control diet. The percent lean or fat mass is calculated by dividing the lean or fat mass by the total weight and multiplying by 100. The addition of the percent lean and percent fat does not add up to one hundred percent because of additional mass from fluid and bone density. Statistics were performed using a 2-way ANOVA with multiple comparisons in GraphPad Prism. * <0.05, **<0.01. Error bars represent standard error of the mean.