Fig 5. Functional annotation of DE genes with shared expression in both cell lines as a result of CKI treatment.
Over-representation analysis was performed to determine a: GO terms for Biological Process, b: KEGG pathways, and c: DO terms for DE genes shared in both cell lines. In nodes for both GO terms and KEGG pathways, node size is proportional to the statistical significance of over-representation. For DO terms, all the enriched terms are statistically significant (p<1 × 10−5) in each category, and the bar length represents the number of expressed genes that map to the term.