Skip to main content
. Author manuscript; available in PMC: 2020 Nov 1.
Published in final edited form as: Biochim Biophys Acta Mol Basis Dis. 2019 Aug 6;1865(11):165527. doi: 10.1016/j.bbadis.2019.08.003

Figure 6: Tyrosine hydroxylase (TH) activity and expression in the olfactory bulb of normotensive and DOCA-salt hypertensive rats following proteasome inhibition and ETA blockade.

Figure 6:

(a) TH activity, (b) TH mRNA, (c) representative western blots and (d) densitometric analysis of total TH and its phosphorylated forms assessed in the OB following MG132 (proteasome inhibitor) (20 μM) and/or BQ610 (selective ETA antagonist) (20 μM) administration as detailed in Materials and Methods. * p<0.05, ** p<0.01 and ***:p<0.001 vs Control; †: p<0.05, ††: p<0.01, and †††: p<0.001 vs. DOCA-Salt; ‡: p<0.05, ‡‡:p<0.01, and ‡‡‡: p<0.001 vs. DOCA-Salt+BQ610; &&: p<0.01 vs. BQ610; #: p<0.05 vs. DOCA-Salt+MG132. Number of animals per experimental group: 4-6.