Table 2. Table of Minor Allele Frequencies (MAF) in different study groups.
High Myopia (HM) | Control Group | |||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
HM with Myopic Maculopathy | HM without Myopic Maculopathy | p-value 1 | HM with CNV | HM without CNV | p-value 2 | No HM | p-value 3 | HW Equili. | ||||||||||||||
Minor Allele | MAF Cohort1 | MAF Cohort 2 | MAF Total | MAF Cohort 1 | MAF Cohort 2 | MAF Total | MAF Cohort 1 | MAF Cohort 2 | MAF Total | MAF Cohort 1 | MAF Cohort 2 | MAF Total | MAF HM | MAF Cohort 1 | MAF Cohort 2 | MAF Total | ||||||
rs11873429 | C | 0.03 | 0.03 | 0.03 | 0.04 | 0.0 | 0.03 | 0.94 | 0.04 | 0.02 | 0.03 | 0.03 | 0.04 | 0.03 | 0.93 | 0.03 | 0.04 | 0.03 | 0.04 | 0.91 | 0.33 | |
rs577948 | G | 0.46 | 0.44 | 0.45 | 0.39 | 0.48 | 0.42 | 0.62 | 0.47 | 0.44 | 0.46 | 0.42 | 0.46 | 0.43 | 0.39 | 0.44 | 0.42 | 0.56 | 0.46 | 0.61 | 0.44 | |
rs669676 | G | 0.53 | 0.54 | 0.54 | 0.43 | 0.52 | 0.46 | 0.11 | 0.54 | 0.46 | 0.5 | 0.49 | 0.46 | 0.46 | 0.26 | 0.48 | 0.42 | 0.38 | 0.41 | 0.07 | 0.17 | |
rs13095226 | C | 0.10 | 0.16 | 0.12 | 0.05 | 0.12 | 0.08 | 0.10 | 0.11 | 0.18 | 0.14 | 0.08 | 0.11 | 0.09 | 0.063 | 0.11 | 0.08 | 0.03 | 0.07 | 0.065 | 0.19 | |
rS644242 | A | 0.04 | 0.05 | 0.04 | 0.05 | 0.06 | 0.05 | 0.75 | 0.04 | 0.04 | 0.04 | 0.04 | 0.07 | 0.05 | 0.81 | 0.04 | 0.07 | 0.05 | 0.06 | 0.27 | 0.58 | |
rs634990 | T | 0.47 | 0.44 | 0.46 | 0.41 | 0.32 | 0.38 | 0.09 | 0.48 | 0.43 | 0.46 | 0.44 | 0.39 | 0.43 | 0.48 | 0.44 | 0.47 | 0.60 | 0.50 | 0.13 | 0.13 | |
rs74315511 | T | 0 | 0 | 0 | 0 | 0 | 0 | - | 0 | 0 | 0 | 0 | 0 | 0 | - | 0 | 0 | 0 | 0 | - | - | |
rs8139305 | G | 0 | 0 | 0 | 0 | 0 | 0 | - | 0 | 0 | 0 | 0 | 0 | 0 | - | 0 | 0 | 0 | 0 | - | - |
HM: High myopia; CNV: Choroidal neovascularization; SD: Standard deviation.
1) P-value comparing HM-No MM with HM-MM.
2) P-value comparing HM-CNV+ with HM-No CNV
3) P-value comparing HM with Control group
Significance p < 0.05