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. 2020 Jul 30;15(7):e0236071. doi: 10.1371/journal.pone.0236071

Table 2. Table of Minor Allele Frequencies (MAF) in different study groups.

High Myopia (HM) Control Group
HM with Myopic Maculopathy HM without Myopic Maculopathy p-value 1 HM with CNV HM without CNV p-value 2 No HM p-value 3 HW Equili.
Minor Allele MAF Cohort1 MAF Cohort 2 MAF Total MAF Cohort 1 MAF Cohort 2 MAF Total MAF Cohort 1 MAF Cohort 2 MAF Total MAF Cohort 1 MAF Cohort 2 MAF Total MAF HM MAF Cohort 1 MAF Cohort 2 MAF Total
rs11873429 C 0.03 0.03 0.03 0.04 0.0 0.03 0.94 0.04 0.02 0.03 0.03 0.04 0.03 0.93 0.03 0.04 0.03 0.04 0.91 0.33
rs577948 G 0.46 0.44 0.45 0.39 0.48 0.42 0.62 0.47 0.44 0.46 0.42 0.46 0.43 0.39 0.44 0.42 0.56 0.46 0.61 0.44
rs669676 G 0.53 0.54 0.54 0.43 0.52 0.46 0.11 0.54 0.46 0.5 0.49 0.46 0.46 0.26 0.48 0.42 0.38 0.41 0.07 0.17
rs13095226 C 0.10 0.16 0.12 0.05 0.12 0.08 0.10 0.11 0.18 0.14 0.08 0.11 0.09 0.063 0.11 0.08 0.03 0.07 0.065 0.19
rS644242 A 0.04 0.05 0.04 0.05 0.06 0.05 0.75 0.04 0.04 0.04 0.04 0.07 0.05 0.81 0.04 0.07 0.05 0.06 0.27 0.58
rs634990 T 0.47 0.44 0.46 0.41 0.32 0.38 0.09 0.48 0.43 0.46 0.44 0.39 0.43 0.48 0.44 0.47 0.60 0.50 0.13 0.13
rs74315511 T 0 0 0 0 0 0 - 0 0 0 0 0 0 - 0 0 0 0 - -
rs8139305 G 0 0 0 0 0 0 - 0 0 0 0 0 0 - 0 0 0 0 - -

HM: High myopia; CNV: Choroidal neovascularization; SD: Standard deviation.

1) P-value comparing HM-No MM with HM-MM.

2) P-value comparing HM-CNV+ with HM-No CNV

3) P-value comparing HM with Control group

Significance p < 0.05