Table 3. Factors independently associated with E/e′ ratio.
| Unadjusted | Model 1 | Model 2 | Model 3 | |
|---|---|---|---|---|
| Β (95% CI) | Β (95% CI) | Β (95% CI) | Β (95% CI) | |
| OH/ECW analyzed as a continuous variable | ||||
| OH/ECW, % | 0.135 (0.071, 0.199) | 0.148 (0.084, 0.211) | 0.152 (0.088, 0.216) | 0.134 (0.057, 0.211) |
| OH/ECW analyzed in tertiles | ||||
| OH/ECW, % | ||||
| tertile 1 | Reference | Reference | Reference | Reference |
| tertile 2 | 0.458 (-1.729, 2.644) | 1.168 (-0.960, 3.297) | 0.783 (-1.262, 2.828) | 0.084 (-2.238, 2.405) |
| tertile 3 | 4.083 (1.896, 6.269) | 4.454 (2.295, 6.613) | 4.404 (2.206, 6.601) | 3.539 (0.973, 6.105) |
| NT-proBNP analyzed in tertiles | ||||
| NT-proBNP, pg/mL | ||||
| tertile 1 | Reference | Reference | Reference | Reference |
| tertile 2 | 1.820 (-0.352, 3.991) | 1.466 (-0.642, 3.574) | 1.170 (-0.911, 3.250) | 0.819 (-1.595, 3.234) |
| tertile 3 | 3.781 (1.610, 5.953) | 3.756 (1.662, 5.850) | 3.663 (1.537, 5.789) | 2.938 (0.199, 5.676) |
Model 1: Adjusted for age and sex.
Model 2: Adjusted for age, sex, cBMI, and SBP.
Model 3: Adjusted for age, sex, cBMI, SBP, calcium, eGFR, and hs-CRP.
OH/ECW tertiles 1, 2, and 3 correspond to <10.60, 10.60–24.68, and >24.68%, respectively.
NT-proBNP tertiles 1, 2, and 3 correspond to <1,143, 1,143–7,087, and >7,087 pg/mL, respectively.
B, β coefficient; cBMI, corrected body mass index; CI, confidence interval; ECW, extracellular water; eGFR, estimated glomerular filtration rate; hs-CRP, high-sensitivity C reactive protein; NT-proBNP, N-terminal prohormone B-type natriuretic peptide; OH, overhydration; SBP, systolic blood pressure.