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. 2020 Jul 30;15(7):e0235640. doi: 10.1371/journal.pone.0235640

Table 4. Factors independently associated with left ventricular mass index.

Unadjusted Model 1 Model 2 Model 3
Β (95% CI) Β (95% CI) Β (95% CI) Β (95% CI)
OH/ECW analyzed as a continuous variable
OH/ECW, % 0.604 (0.330, 0.878) 0.684 (0.402, 0.966) 0.725 (0.430, 1.020) 0.525 (0.157, 0.893)
OH/ECW analyzed in tertiles
OH/ECW, %
tertile 1 Reference Reference Reference Reference
tertile 2 16.762 (7.374, 26.151) 16.389 (6.882, 25.986) 15.610 (6.060, 25.159) 12.194 (1.374, 23.013)
tertile 3 17.353 (7.965, 26.742) 14.412 (9.218, 28.505) 19.113 (8.852, 29.373) 13.225 (1.266, 25.183)
NT-proBNP analyzed in tertiles
NT-proBNP, pg/mL
tertile 1 Reference Reference Reference Reference
tertile 2 17.911 (8.919, 26.902) 18.591 (9.639, 27.544) 19.264 (10.213, 28.315) 16.494 (5.881, 27.107)
tertile 3 21.155 (12.164, 30.146) 21.353 (12.459, 30.248) 23.098 (13.849, 32.347) 15.981 (3.944, 28.018)

Model 1: Adjusted for age and sex.

Model 2: Adjusted for age, sex, cBMI, and SBP.

Model 3: Adjusted for age, sex, cBMI, SBP, calcium, eGFR, and hs-CRP.

OH/ECW tertiles 1, 2, and 3 correspond to <10.60, 10.60–24.68, and >24.68%, respectively.

NT-proBNP tertiles 1, 2, and 3 correspond to <1,143, 1,143–7,087, and >7,087 pg/mL, respectively.

B, β coefficient; cBMI, corrected body mass index; CI, confidence interval; ECW, extracellular water; eGFR, estimated glomerular filtration rate; hs-CRP, high-sensitivity C reactive protein; NT-proBNP, N-terminal prohormone B-type natriuretic peptide; OH, overhydration; SBP, systolic blood pressure.