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. 2020 Jul 30;15(7):e0236758. doi: 10.1371/journal.pone.0236758

Table 2. Treatment regimens for assessed anti-chlamydial antibiotics in koalas.

Antibiotic (Manufacturer) Concentration Dose rate Frequency Route Duration Comments Ref
Azithromycin (Pfizer) 100 mg/mL 20 mg/kg SID IV 3 days Diluted to a 2 mg/mL solution in sterile 0.9% saline and infused over 30 minutes in sedated koalas. Child dose rate. [14]
Chloramphenicol (Ceva) 150 mg/mL 60 mg/kg SID S/C 28 days Ready to use; rotated between sites; dose rate previously used to successfully treat chlamydiosis in koalas. [15]
Doxycycline LA (Vetafarm) 50 mg/mL 5 mg/kg Every 7 days IM or S/C 28 days Diluted 50:50 in saline; less tissue reaction if given s/c, rotated between sites; small animal dose rates. [16]
Enrofloxacin (Bayer) 50 mg/mL 10 mg/kg loading dose; then 5 mg/kg SID S/C 28 days Diluted 50:50 in saline; rotated between sites; small animal dose rates. [17]
Florfenicol (Merck) 300 mg/mL 20 mg/kg Every 2 days S/C 28 days Ready to use, domestic animal dose rate. [18]

LA = long-acting formulation; SID = once daily, S/C = Subcutaneous, IV = Intravenous, IM = Intramuscular.