Table 2. Treatment regimens for assessed anti-chlamydial antibiotics in koalas.
Antibiotic (Manufacturer) | Concentration | Dose rate | Frequency | Route | Duration | Comments | Ref |
---|---|---|---|---|---|---|---|
Azithromycin (Pfizer) | 100 mg/mL | 20 mg/kg | SID | IV | 3 days | Diluted to a 2 mg/mL solution in sterile 0.9% saline and infused over 30 minutes in sedated koalas. Child dose rate. | [14] |
Chloramphenicol (Ceva) | 150 mg/mL | 60 mg/kg | SID | S/C | 28 days | Ready to use; rotated between sites; dose rate previously used to successfully treat chlamydiosis in koalas. | [15] |
Doxycycline LA (Vetafarm) | 50 mg/mL | 5 mg/kg | Every 7 days | IM or S/C | 28 days | Diluted 50:50 in saline; less tissue reaction if given s/c, rotated between sites; small animal dose rates. | [16] |
Enrofloxacin (Bayer) | 50 mg/mL | 10 mg/kg loading dose; then 5 mg/kg | SID | S/C | 28 days | Diluted 50:50 in saline; rotated between sites; small animal dose rates. | [17] |
Florfenicol (Merck) | 300 mg/mL | 20 mg/kg | Every 2 days | S/C | 28 days | Ready to use, domestic animal dose rate. | [18] |
LA = long-acting formulation; SID = once daily, S/C = Subcutaneous, IV = Intravenous, IM = Intramuscular.