Table 1. Body weight, femoral geometry, mineral content and density, and mechanical properties in 8 week old male and female STAT3-cKO mice and their littermate controls (CN).
| Females | Males | |||
| CN (n = 11) | STAT3-cKO (n = 12) | CN (n = 9) | STAT3-cKO (n = 10) | |
| Body weight (g) | 18.01±0.65 | 18.24±1.49 | 22.10±0.95 | 22.93±1.96 |
| Femur Length (mm) | 14.02±0.53 | 14.56±0.72 | 14.62±0.35 | 15.35±0.73 |
| Femur BMD (g/cm2) | 0.043±0.003 | 0.039±0.003* | 0.046±0.004 | 0.046±0.007 |
| Femur BMC (g) | 0.016±0.003 | 0.014±0.002* | 0.019±0.002 | 0.018±0.004 |
| Femoral Midshaft Geometry and Mechanical Properties (8 weeks) | ||||
| Tt.Ar (mm2) | 1.53±0.07 | 1.47±0.10 | 1.69±0.09 | 1.78±0.20 |
| Ct.Ar (mm2) | 0.56±0.03 | 0.53±0.05 | 0.68±0.05 | 0.68±0.12 |
| Ma.Ar (mm2) | 0.97±0.05 | 0.94±0.06 | 1.01±0.06 | 1.10±0.10 |
| Ct.Th (mm) | 0.14±0.01 | 0.14±0.01 | 0.17±0.01 | 0.16±0.02 |
| Ultimate Force (N) | 10.07±1.3 | 9.81±2.08 | 12.41±1.65 | 14.29±3.09 |
| Stiffness (N/mm) | 49.9±8.24 | 46.35±12.24 | 57.94±9.51 | 71.81±20.6 |
| Total Work (mJ) | 11.24±2.67 | 8.63±2.7* | 13.87±4.44 | 13.23±5.23 |
BMD: bone mineral density; BMC: bone mineral content.
Tt.Ar: total cross sectional area. Ct.Ar: cortical area. Ma.Ar: marrow area. Ct.Th: Cortical thickness.
*: p < 0.05 v.s. the same sex CN.