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. 2020 Aug;26(8):1792–1800. doi: 10.3201/eid2608.191499

Table 5. Association between clinical and confirmed peripheral and optical neuropathy and patient characteristics among 57 patients with multidrug-resistant tuberculosis, Pitié-Salpêtrière Hospital, Paris, France, 2011–2016*.

Characteristic Clinical neuropathy
Confirmed neuropathy
Value p value* Value p value*
Age, OR (95% CI)† 1.83 (0.9–3.7) 0.09 1.66 (0.8–3.3) 0.14
Immunosuppression treatment, OR (95% CI) 0.91 (0.3–2.7) 0.98 2.1 (0.7–6.2) 0.18
History of intravenous drug use, OR (95% CI) 0.43 (0.5–4.9) 0.43 1.79 (0.6–5.4) 0.30
Opioid substitution therapy, OR (95% CI) 1.6 (0.4–6.1) 0.49 1.92 (0.5–7) 0.32
Albumin, g/L 0.81 (0.4–1.8) 0.61 1.01 (0.5–2.2) 0.98
Linezolid treatment duration, mo 0.47 (0.2–1.2) 0.10 1.11 (0.5–2.7) 0.82
Culture conversion, d 0.93 (0.8–1.1) 0.35 1.15 (0.9–1.4) 0.21
Trough linezolid concentration >2 mg/L 2.07 (0.6–7.3) 0.26 0.83 (0.3–2.7) 0.76

*p values from univariate logistic models. OR, odds ratio.
†Risk based on age increase by 10-y intervals.