Table 1. Patient characteristics.
Variables/categories | S-1/cisplatin arm | Paclitaxel/cisplatin arm | |||||||
---|---|---|---|---|---|---|---|---|---|
Cohort 1 (n = 41) | Cohort 2 (n = 23) | Cohort 1 (n = 42) | Cohort 2 (n = 23) | ||||||
No. | % | No. | % | No. | % | No. | % | ||
Age (years) | Median (range) | 65 (32–79)* | 66 (41–79)* | 66 (43–80)* | 65 (44–76)* | ||||
Gender | Male | 26 | 63 | 15 | 65 | 32 | 76 | 19 | 83 |
Female | 15 | 37 | 8 | 35 | 10 | 24 | 4 | 17 | |
Performance status | 0 | 41 | 100 | 23 | 100 | 40 | 95 | 23 | 100 |
1 | 0 | 0 | 0 | 0 | 2 | 5 | 0 | 0 | |
Macroscopic type | Non-scirrhous | 30 | 73 | 14 | 61 | 27 | 64 | 14 | 61 |
Type 4/giant type 3 | 11 | 27 | 9 | 39 | 15 | 36 | 9 | 39 | |
Histological type | Differentiated | 17 | 41 | 7 | 30 | 19 | 45 | 11 | 48 |
Undifferentiated | 24 | 59 | 16 | 70 | 23 | 55 | 12 | 52 | |
Clinical T | T2 | 0 | 0 | 0 | 0 | 1 | 2 | 0 | 0 |
T3 | 2 | 5 | 1 | 4 | 4 | 10 | 1 | 4 | |
T4a | 36 | 88 | 20 | 87 | 32 | 76 | 21 | 91 | |
T4b | 3 | 7 | 2 | 9 | 5 | 12 | 1 | 4 | |
Clinical N | N0 | 5 | 12 | 4 | 17 | 7 | 17 | 5 | 22 |
N1 | 19 | 46 | 11 | 48 | 16 | 38 | 8 | 35 | |
N2 | 17 | 41 | 8 | 35 | 18 | 43 | 9 | 39 | |
N3 | 0 | 0 | 0 | 0 | 1 | 2 | 1 | 4 | |
Clinical M | Negative | 35 | 85 | 21 | 91 | 34 | 81 | 21 | 91 |
Positive | 6 | 15 | 2 | 9 | 8 | 19 | 2 | 9 | |
Site of M | CY1** and P0*** | 6 | 100 | 2 | 100 | 7 | 88 | 2 | 100 |
Para-aortic nodes | 0 | 0 | 0 | 0 | 1 | 12 | 0 | 0 |
*Expressed as median (range), **CY1; positive for peritoneal lavage cytology, ***P0; negative for peritoneal dissemination.