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. 2020 Jul 28;11(30):2889–2905. doi: 10.18632/oncotarget.27587

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Copyright: Narvaez et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License 3.0 (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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(A) Oncoprint showing genomic alterations in VDR, HAS1, HAS2, and HAS3 in 1904 human breast tumors. Each column of light grey bars in this scheme represents one case of human breast cancer; colored bars indicate specific types of genomic alterations as indicated in the legend. (B) Kaplan Meier analysis of overall survival in METABRIC dataset stratified by HAS2 alterations. (C) HAS2 alterations according to breast cancer subtype. (D) Correlation between HAS2 and GFPT2 expression. All data were calculated from publicly accessible METABRIC database at cBio Cancer Genomics Portal.