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. Author manuscript; available in PMC: 2021 Aug 1.
Published in final edited form as: Trends Cancer. 2020 May 22;6(8):688–701. doi: 10.1016/j.trecan.2020.04.009

Figure 2. Mitochondrial stress response promotes cancer growth, progression and therapeutic resistance in cancer.

Figure 2.

A schematic describing how different stresses induce mitochondrial dysfunction leading to the activation of the mitochondrial stress response, restoration of mitochondrial integrity, cancer cell survival, which subsequently promotes tumor growth and progression.