Fig. 4. M2 treatment induces DDR-related gene expression including RAD51.
a RNA from viable H929 MM cells treated with M2 under sub-lethal conditions were analyzed using the TaqMan® human DNA Repair pathway array. Transcripts were normalized by geomean of internal controls, and fold changes in M2-treated relative to control (cnt) groups are shown. b-c Cell lysates were made from various M2-treated MM cell lines for immunoblotting to determine protein levels of RAD51.