Fig. 2.

Profile of fecal SCFA (butyric acid and propionic acid) from HFD mice after 12 weeks of treatment with IX mixed into diets.

Effect of the treatment with IX for 12 weeks on the profile of SCFA in HFD-fed mice. Fecal contents of each SCFA are quantified and described as relative values divided by those of the ND group and presented as means ± SE of 10 mice. *p<0.05 between the ND and HFD groups (Student’ t-test). #p<0.05 between the HFD and other groups (Dunnett’s test). SCFA: short-chain fatty acid; IX: isoxanthohumol; ND: normal diet; HFD: high-fat diet; HFD + 0.01% IX: HFD containing a final concentration of 0.01% IX; HFD + 0.03% IX: HFD containing a final concentration of 0.03% IX; HFD + 0.1% IX: HFD containing a final concentration of 0.1% IX.