Fig. 3.

Microbial composition of the cecal contents after oral administration of isoxanthohumol and tea catechins for 8 weeks at the (A) phylum and (B) genus levels for Akkermansia muciniphila as well as (C) individual data. Data are presented as means of 8 mice. For (A) phylum level, #p<0.05 between the HFD and other groups (Dunnett’s test). For (B) genus level, #p<0.01 between the HFD and other groups (Dunnett’s test). IX: isoxanthohumol; ND: normal diet; HFD: high-fat diet; HFD+C: HFD and tea catechins 300 mg/kg; HFD+IX-M: HFD and medium-dose (60 mg/kg) IX; HFD+IX-H: HFD and high-dose (180 mg/kg) IX.