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. 2020 Jul 30;5:70. doi: 10.1038/s41541-020-00218-y

Fig. 3. Humoral responses against BTV and RVFV elicited by MVA recombinant vaccines 2 weeks post booster in mice.

Fig. 3

Induction of virus-neutralizing antibodies against BTV a and RVFV b in animals immunized with MVA recombinant vaccines by plaque reduction neutralization assay. The columns represent the mean of the group and error bars that indicate the SD. Cutoff: 0.69 (log 5). c Induction of IgG VP2 antibodies by indirect ELISA in MVA-GnGc-VP2-vaccinated animals. Three dilutions of sera were tested (x-axis) and lines represent media. d Induction of IgG NS1 antibodies by indirect ELISA in MVA-GnGc-NS1- and MVA-GnGc-NS1-Nt-vaccinated mice. Three dilutions of sera were tested (x-axis). Lines represent means and error bars the SD. Statistical differences were calculated by Mann–Whitney nonparametric tests; *p ≤ 0.05.