Fig. 5. Protection conferred by dual MVA recombinant vaccines against BTV in IFNAR^(−/−) mice.

a Viremia at 5 d.p.i. expressed as log PFU/ml of mice at day 5 after challenge with 500 PFU of BTV-4. Differences between groups were calculated by multiple t-test analysis using the Sidak–Bonferroni method. b Survival rates of vaccinated and non-vaccinated mice after challenge. Survival data were analyzed using a log-rank test with mice grouped by immunization strategy; *p ≤ 0.05.