Fig. 4. Model of growing epithelial shells.

a Reduced volume of growing shells as a function of cell number, based on 25 instances. b–e Shell shapes at N_c = 300 and (α, β) = (1.2, 1.2), (1.1, 0.5), (0.5, 1.1),  and (0.7, 0.5), respectively. f Growing shell with (α, β) = (0.7, 0.5) at 100-, 200-, and 300-cell stage in absence of active T1 transitions. g Growing shell at the same α and β but with active T1 transitions.