Table 1.

M-model and CM-model properties.

Model features	iJB792	iECW1372	iML1515	iYO844	iYali4	iCZ-Se-EcW(2157)	iCZ-Se-EcK-12(2152)	iCZ-Se-Bs(1629)	iCZ-Se-Yl(1686)
Genes	792	1273	1366	844	901	2157	2152	1629	1686a
Reactions	897	2477	2583	1250	1985	3301	3161	1921	2739
Metabolites	792	1111	1805	844	1684	2688	2547	1732	2399
Microorganism	Synechococcus elongatus PCC7942	E. coli W	E. coli K-12 MG 1655	Bacillus subtilis	Yarrowia lipolytica	S. elongatus–E. coli W	S. elongatus–E. coli K-12	S. elongatus–B. subtilis	S. elongatus–Y. lipolytica
Conditions	PA	A, AN	A, AN	A	A	P, A	P, A	P, A	P, A
Reference	Broddrick et al.32	Monk et al.28	Monk et al.29	Oh et al.30	Kerkhoven et al.31	This study	This study	This study	This study

The first row contains the names of the model. Each model can be simulated under different conditions: Phototroph models can be simulated under photoautotrophy (P), heterotrophy (H), and/or mixotrophy (M). Heterotroph models can be simulated under aerobic (A) and/or anaerobic (AN) conditions.

Organelles: c cytoplasm, cx carboxysome, r endoplasmic reticulum, g Golgi apparatus, l liposome, p periplasm, m mitochondria, n nucleus, x peroxisome, t thylakoid, and v vacuole.

*The consumption of ethanol was included into the Yarrowia model, adding genes and reactions.