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. 2020 Jul 30;10:12901. doi: 10.1038/s41598-020-69765-7

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Longitudinal observation of the hyaloid, retinal, and choroidal vasculatures in the control and the OIR eyes. (a,b) En face OCTA images of the three vasculatures in the control and OIR eyes (same eyes shown in Fig. 2), respectively. Artifacts enclosed by the red-dotted contours are caused by spurious reflections from the imaging optics of the OCTA system. Scale bars: 200 μm. (c–f) Correlation analyses between the hyaloid vessel volumes and the retinal vessel densities in the control (black) and the OIR (green) eyes. *P < 0.05 and ****P < 0.0001. (g–j) Correlation analyses between the hyaloid vessel volumes and the choroidal vessel densities in the control (black) and the OIR (green) eyes.