FIGURE 3.

Equine model of persistent AF—AF progression over 1 month: (a) overview of the total number of horses in self‐sustained AF on respective procedure days. (b) Representative ECG (10 s) traces prior to XAF‐1407 administration on day 11. (c) AF cycle length (AFCL) as a measure of electrical remodelling progression over time prior to XAF‐1407 infusion. (d) Atrial fibrillatory rate (AFR) as a measure of electrical remodelling progression over time prior to XAF‐1407 infusion. Data presented as individual time course per horse. *P < .05, significantly different as indicated. AF, atrial fibrillation; N, number of horses; n, number of measurements