Atrial fibrillatory rates (AFRs) following XAF‐1407 infusion: (a) the depicted ECG traces show the transformation from fine to more coarse fibrillation waves in response to drug administration in 5‐s ECG traces at day 11 (5 min prior to drug administration and 10 min after end of drug administration) versus day 17 (5 min prior to drug administration and 10 min after end of drug administration), however only subsequently leading to cardioversion on day 11. (b–f) Influence of XAF‐1407 administration on AFR for horse #8, representative for the study population: (b) procedure day 3; (c) procedure day 5; (d) procedure day 11; (e) procedure day 17; and (f) procedure day 29. (g) Influence of XAF‐1407 on AFR from start of injection to end of injection at all procedure days (N = 6, n = 6). *P < .05, significantly different as indicated. N, number of horses; n, number of measurements