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. 2020 Jul 24;11:716. doi: 10.3389/fpsyt.2020.00716

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Copyright © 2020 Niu, Cao and Ji

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of RSV on the protein expression of SIRT1 and BDNF and CREB phosphorylation in the hippocampus of MK-801 treated rats. (A) Western blot was used to measure the protein expression of SIRT1, p-CREB, CREB, and BDNF in hippocampus. GAPDH was used as loading control. Relative expression was normalized to control group. n = 6 in each group. Data were presented as mean ± SD. F ratios: (B) 21.96 (3.00, 19.71), (C) 26.80 (3.00, 15.08), (D) 8.625 (3.00, 11.37). *p < 0.05, **p < 0.01, and ***p < 0.001 between the indicated groups.